Shelnard

[Idle Miscreant]

The Holmes/Watson Sheldon/Leonard similarities are so manifold that I can't even be arsed enumerating them.

There are of course certain differences between Leonard and Watson, insofar as I'm fairly sure John at no point sabotaged Sherlock's experiments, misled him into thinking he'd cracked a great scientific mystery and achieved the dream of his lifetime, then waved off his friend's devastation in favour of trying to have sex with a pretty blonde.

But aside from that, they are quite similar.